November 23, 2021

There are currently no drugs that improve the heart’s repair process after a heart attack.

Using cardiac muscle cells derived from human stem cells, new UCLA research published today in the Journal of Clinical Investigation suggests how the repair process could be modulated in cardiac muscle to improve outcomes after a heart attack–the study also identifies specific molecular targets for new drugs.

The study’s senior author, Arjun Deb, MD is a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, and a UCLA professor of cardiology and a professor our Department of Molecular, Cell, and Developmental Biology (MCDB). Other MCDB researchers include Utpal Banerjee, Matteo Pellegrini, and Mark Sharpley.

You can read more here, in this UCLA Newsroom Research Brief.