A new UCLA study provides insight into the slower repair and recovery process in aging muscles.
This latest study – conducted in mice – shows that certain molecular changes in the muscle stem cells of older individuals are associated with a reduced ability to repair damaged tissue; however, it seems that these same changes are also associated with protective adaptations that help these stem cells persist into older age.
Understanding what controls these trade-offs is key to understanding aging at the level of our tissues.
The study was led by UCLA researchers, Jengmin Kang and Daniel Benjamin, working with Dr. Thomas Rando – a professor of molecular, cell, and developmental biology and director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.
Read more about this research in the UCLA Newsroom.